What are the benefits of metabiotic?

In contrast to probiotics Actoflor-S does not contain any live or dead bacteria, foreign to your body; it does not contain microbes at all. Actoflor-S works on quite another principle.

The main aim to be resolved by Actoflor-S is to help your own microbiota to cope with the disease.

Actoflor-S includes 12 compounds – metabolites of probiotic bacteria – cumulative effect is aimed to stimulate your own microbiota.

Differences in the mechanisms of action of probiotics and metabiotics

Passes through the aggressive gastric environment into the intestine
Use of the active metabolites by resident microbes and their proliferation
Recovery of gastrointestinal tract and strengthening the immune system
PROBIOTIC
Passes through the aggressive gastric environment into the intestine
Adaptation of the surviving microbes
Microbial proliferation
Synthesis and release of signaling substances
Use of the substances by resident microbes and their proliferation
Recovery of gastrointestinal tract and strengthening the immune system
Metabiotic acts faster than probiotic bypassing the a stage of adaptation
METABIOTIC

Actoflor-S — a new generation of metabiotic

2016
2016
Actoflor-S
Launch of the first Russian metabiotic based on the metabolites of probiotic strain E. coli M-17
2013
2013
Development the metabiotics concept
Russian scientist B.A. Shenderov suggested the idea of metabiotics as a natural development of the probiotics concept
2007
2007
The first synthetic metabiotiс
Launch of the first European metabiotiс based on butyric acid
2007
2007
Metabiotics
Gary B. Huffnagle and Sarah Wernick described metabiotics as beneficial metabolic products of probiotic bacteria. These products create the most favorable environment for bacteria, provide the nutrition for the intestinal epithelium supporting the integrity of the intestinal barrier and stimulate inflammatory function of the human immune system
1995
1995
Synbiotics
G. Gibson and M. Roberfroid suggested the term "Prebiotics" and "Synbiotics" (for the combination of pro- and prebiotics)
1965
1965
Probiotics
Lilly and Stilwell first suggested the term "probiotics"; probiotics as opposed to antibiotics, are microbial factors that stimulate the growth of other organisms
1950-e
1950-e
Prebiotics
The discovery of substances with bifidogenic effect
1930
1930
Colibacterin
Russian microbiologist L.G. Peretz has developed a biological product based on the culture of E. coli strain M-17, isolated from healthy human intestine
1917
1917
Escherichia coli Nissle 1917
Alfred Nissle identified strain of E. coli from healthy bowel of soldier, later served as the basis for the creation of probiotic "Mutaflor"
1906
1906
Lactobacillin
The company Le Ferment (Paris) with the support of I.I. Mechnikov released lactic culture (powder) Lactobacilline, to prepare yogurt at home, and for the treatment of various digestive diseases
1904
1904
Dairy products
Nobel laureate I.I. Mechnikov first linked consumption of dairy products with lifetime of inhabitants of some regions in Bulgaria
Why the metabiotiс is beneficial and how it was first developed, see the article: Aсtoflor®-S - the first metabiotiс of the twenty-first century