Frequently Asked Questions

Why do so many components included in the metabiotic Actoflor-S?
Activity of metabiotic Actoflor-S depends on the collective effects of all 12 components. Numerous experiments have shown that the removal of at least one of the components or change its concentration leads to a decrease or metabiotic activity or reliability of its action.
What function is performed by the components of Actoflor-S?
Carboxylic acids are food for the bacteria and host cells and also have a regulatory effect on them. First of all, they act upon the own microbiota cells. Carboxylic acids and other metabolites, depending on their concentration and composition, have a stimulatory effect on the growth and activity of some microorganisms and inhibit the development of others. Generally, the effect is directed at optimizing the functions of all microbiota.

Acetate (acetic acid salt), and lactate (lactic acid salt) adjust the pH level, motion and secretory activity of the intestine, have laxative and antimicrobial effects.

Some of amino acids (glutamic acid, methionine, lysine, leucine, etc.) have a pronounced stimulating effect in relation to normal flora and the probiotic bacteria. Glycine regulates the amount of bacteria cells.
Can I take Actoflor-S during antibiotic therapy?
Actoflor-S doesn't contain bacteria or their components. It includes only the metabolites of bacteria, obtained by chemical synthesis, so Actoflor-S retains its effectiveness during antibiotic therapy. Thus, there are no contraindications for concurrent use of Actoflor-S and antibiotics. However, for the concurrent use you should consult with a physician.
Is the presence of bacteria necessary in preparation for restoring microbiota?
Can one take Actoflor-S during antibiotic therapy? Actoflor-S doesn't contain bacteria or their components. It includes only the metabolites of bacteria, obtained by chemical synthesis, so Actoflor-S retains its effectiveness during antibiotic therapy. Thus, there are no contraindications for concurrent use of Actoflor-S and antibiotics. However, for the concurrent use you should consult with a physician. Is the presence of bacteria necessary in preparation for restoring microbiota? Probiotics contain bacteria that often have no effect because the majority of microorganisms don't survive in the stomach and the upper intestine, and the survivors rejected by resident microbiota. Furthermore, probiotics themselves can cause side effects such as allergy or diarrhea. At the same time co-administration of antibiotics with probiotics is not very effective, because the latter inhibit the activity of the bacteria. Besides, it is impossible to accurately determine the optimum number of bacteria to provide necessary effect. Therefore it is preferred to use such products for stimulating the microbiota, which don't contain bacteria or their components.
Can I take Actoflor-S with high stomach acidity?
Patients with high acidity can take Actoflor-S. Undiluted Actoflor-S is slightly acidic solution with pH 5.7. Most of the food are significantly more acidic. For example, the pH of apples - 3.5-4.0; beer and tomato juice – 4.0-5.0; potatoes – 5.6- 6.0.
Where is Actoflor-S made?
Actoflor-S is made on the newest high tech European equipment of SOLOPHARM plant in St. Petersburg. SOLOPHARM– is the leader of producing liquid drugs in Russia. The largest pharmaceutical plant which produces sterile liquid dosage forms according to GMP standards.
Is Actoflor-S a medicine?
Actoflor-S is not a medicine. It is registered in the Russian Federation as a dietary supplement.
What might happen if I interrupt taking Actoflor-S for a few days?
If you forget to take Actoflor-S, you do not need to take a few doses at a time, just keep intake as usual.
Can I give Actoflor-S to my child?
We do not recommend Actoflor-S for children. Actoflor-S is not contraindicated in children, but currently the regimen for children is being developed.